AMA: Normal Labs But Still Stuck? Insulin, PMS, Fibroids + Gut Flares Explained
Dr. Jolene BrightenPublished on April 30, 2026
Summary authored by editor@wellifi.com
TLDR Summary
In this episode of The Dr. Jolene Brighten Show, Dr. Brighten addresses common women's health issues, focusing on hormonal health, postpartum anxiety, and the complexities of managing conditions like fibroids and IBD. Practical recommendations and insights from her upcoming book on ADHD in women are also shared.
Key Points
- Elevated fasting insulin can indicate insulin resistance, even when other markers are normal.
- SSRIs can help relieve severe PMS symptoms when necessary.
- Micronized progesterone can help with postpartum anxiety.
- Nutrition and sleep are critical for postpartum recovery.
- Progesterone may help some women with fibroids but requires careful monitoring.
- Dietary adjustments can support digestion during the luteal phase.
The Dr. Jolene Brighten Show: Hormone Health AMA
Welcome to a special episode of The Dr. Jolene Brighten Show, where we dive deep into important health topics that often get brushed aside. In today’s Ask Me Anything (AMA), I address common yet crucial questions about women’s health, including hormonal issues, postpartum anxiety, and the effects of various compounds on our bodies. I also share insights from my upcoming book on ADHD in women, available for pre-order now.
Understanding Elevated Fasting Insulin
One question that often arises is why doctors don’t focus on elevated fasting insulin when other markers like hemoglobin A1C and fasting glucose appear normal. Elevated fasting insulin, known as hyperinsulinemia, can indicate insulin resistance, often developing before glucose levels show abnormality. Healthcare providers typically prioritize diabetes screening, overlooking fasting insulin levels that may signal future metabolic issues.
Key Points:
- Elevated fasting insulin can indicate insulin resistance, even when other markers are normal.
- Improving metabolic health involves looking at fasting insulin alongside other factors like sleep and stress.
The Complications of PMS and PMDD
Another significant topic discussed was the use of SSRIs for severe PMS symptoms. It's crucial to differentiate between PMS and premenstrual dysphoric disorder (PMDD). SSRIs can be beneficial during the luteal phase, especially for those with PMDD, which often involves heightened hormone sensitivity and mood symptoms.
Key Points:
- SSRIs can help relieve severe PMS symptoms when necessary.
- Understanding the distinction between PMS and PMDD is vital for effective treatment.
Postpartum Recovery: Addressing Anxiety and Depression
Postpartum anxiety and depression are prevalent yet often overlooked. Natural recovery options include micronized progesterone, magnesium, and ensuring adequate nutrition. It’s essential to focus on the mother’s mental health as it significantly impacts the newborn’s well-being.
Key Points:
- Micronized progesterone can help with postpartum anxiety.
- Nutrition and sleep are critical for postpartum recovery.
Managing Fibroids with Progesterone
When asked about the safety of using progesterone with fibroids, the answer is nuanced. While progesterone can sometimes aid in managing symptoms, it may also stimulate fibroid growth. Individualized treatment based on the size and symptoms of fibroids is essential.
Key Points:
- Progesterone may help some women with fibroids but requires careful monitoring.
- Individualized treatment plans are crucial for managing fibroids effectively.
Supporting Digestion During the Luteal Phase
The luteal phase can impact digestion, particularly for those with inflammatory bowel disease (IBD). Adjustments such as consuming cooked vegetables, smaller meals, and ensuring hydration can alleviate symptoms during this time.
Key Points:
- Dietary adjustments can support digestion during the luteal phase.
- Monitor IBD symptoms closely, especially during hormonal fluctuations.
Conclusion
Understanding hormonal health is complex but crucial for managing many aspects of women's health. By tracking symptoms and recognizing red flags, women can better advocate for their health. Thank you for joining me today, and don’t forget to like, subscribe, and share this episode with others who might benefit!