Canker Sores, Mold Toxicity & Cast Iron: Your Health Questions Answered | Dr. Will Cole AMA
Dr. Will ColePublished on May 18, 2026
Summary authored by editor@wellifi.com
TLDR Summary
Canker sores can signal underlying health issues, while mold exposure may exacerbate conditions like MCAS. Effective management involves dietary support, natural remedies, and addressing environmental factors.
Key Points
- Canker sores can indicate underlying health issues, such as autoimmune conditions and nutrient deficiencies.
- Manuka honey and turmeric gel can be effective natural remedies for canker sores.
- Mold exposure may exacerbate conditions like MCAS, and addressing it is crucial for health.
- Autoimmune conditions may require dietary support, including blood-building foods and immune-modulating peptides.
Understanding Canker Sores and Their Causes
Canker sores, also known as recurrent aphthous stomatitis, can be a painful and frustrating issue for many. In a recent episode of the Art of Being Well podcast, Dr. Will Cole and his team addressed several health questions, including those related to canker sores, mold toxicity, and autoimmune conditions. This blog post will summarize the insights shared during the episode and provide practical recommendations for managing these conditions.
Canker Sores: What You Need to Know
Canker sores can occur due to various reasons, including:
- Accidental biting of the lip
- Dental work or braces
- Stress and immune system responses
While some people may experience canker sores infrequently, others might have them occur more regularly. Dr. Cole emphasizes that canker sores can serve as a "check engine light" indicating potential underlying health issues, such as:
- Autoimmune conditions (e.g., ulcerative colitis, Crohn's, celiac disease, lupus)
- Nutrient deficiencies (e.g., iron, folate, B12, zinc)
Recommendations for Managing Canker Sores
To alleviate pain and prevent future occurrences of canker sores, consider the following recommendations:
- Manuka Honey: Known for its wound-healing properties, Manuka honey can outperform steroids in clinical studies. It can be used topically as a salve or made into a mouth rinse.
- Turmeric Gel: Turmeric has anti-inflammatory properties and can be made into a gel to apply to canker sores.
- Dietary Adjustments: Consuming a diet rich in iron and B vitamins, and addressing any nutrient deficiencies through testing can be beneficial.
- Probiotics: A good quality probiotic can help support the oral microbiome and the immune system.
Mold Toxicity and Health Concerns
Another key topic addressed in the podcast was mold toxicity and its impact on health, particularly concerning mast cell activation syndrome (MCAS). Mold exposure can trigger histamine responses and exacerbate conditions like MCAS.
Dr. Cole noted that while mold is often dismissed as a minor concern, it can significantly affect those who are sensitive. Symptoms may include:
- Increased inflammation
- Worsened allergy symptoms
- Autoimmune responses
Addressing Mold Toxicity
For individuals dealing with mold toxicity, consider the following steps:
- Remove the Source: Identify and remediate any mold in your living or working environments.
- Support Detoxification: Nutritional support, including glutathione and activated charcoal, can help detoxify the body.
- Mast Cell Stabilizers: Compounds like quercetin and vitamin C can help stabilize mast cells and reduce histamine responses.
Functional Medicine Insights on Autoimmune Conditions
Dr. Cole also discussed autoimmune conditions such as acquired autoimmune thrombocytopenia. Individuals with multiple autoimmune diagnoses may benefit from comprehensive testing to identify underlying triggers, including viral infections and nutrient deficiencies.
Recommendations for supporting autoimmune conditions include:
- Dietary Support: Incorporate blood-building foods like papaya leaf extract, chlorella, and organ meats.
- Support Immune Function: Peptides like Thymosin Alpha can help modulate the immune response.
Using Cast Iron Cookware Safely
A listener raised concerns about the safety of seasoning cast iron cookware, particularly regarding the breakdown of fatty acids in oils. Dr. Cole reassured that using high-quality oils with higher smoke points, such as avocado or refined coconut oil, is generally safe. Additionally, cooking with acidic mediums can help leach iron into foods.
Key Takeaways
- Canker sores can be a sign of underlying health issues, including autoimmune conditions and nutrient deficiencies.
- Addressing mold exposure is crucial for those suffering from MCAS or allergies.
- Support for autoimmune conditions may include dietary adjustments, nutritional supplementation, and addressing environmental factors.
- Using cast iron cookware is safe when properly seasoned and maintained, and it can even help increase dietary iron intake.
Conclusion
Understanding the root causes of health issues, such as canker sores, mold toxicity, and autoimmune conditions, is essential for effective management. By applying the insights from Dr. Will Cole and his team, individuals can take proactive steps to support their health and well-being.
