Essentials: Breathing for Mental & Physical Health & Performance | Dr. Jack Feldman
Huberman LabPublished on November 13, 2025
Summary authored by editor@wellifi.com
TLDR Summary
In this episode, Dr. Jack Feldman discusses the mechanics of breathing, its connection to brain function and emotional regulation, and the importance of breathing practices for mental health. Additionally, the potential benefits of magnesium threonate for cognitive function are explored.
Key Points
- Breathing is essential for oxygen intake and carbon dioxide removal, regulated by the diaphragm and neural centers in the brain.
- Both nasal and mouth breathing serve distinct functions, with nasal breathing being more efficient at rest.
- Deep breathing helps maintain lung health by preventing alveolar collapse.
- Breathing practices can significantly influence emotional regulation and cognitive function.
- Supplements like magnesium threonate may enhance cognitive performance and support mental health.
Understanding the Science of Breathing: Insights from Dr. Jack Feldman
Welcome to Huberman Lab Essentials, where we revisit past episodes for the most potent and actionable science-based tools for mental health, physical health, and performance. In this episode, Professor Andrew Huberman speaks with Dr. Jack Feldman, a leading expert in the field of respiration and its connection to brain function. Together, they delve into the intricacies of breathing, its physiological significance, and its impact on mental and emotional well-being.
The Mechanics of Breathing
Breathing involves a complex interplay of mechanical and neurological processes. Our bodies require oxygen for metabolism, and as this oxygen is utilized, carbon dioxide is produced, necessitating its removal to maintain the acid-base balance of the blood. The primary muscle responsible for inhalation is the diaphragm, which contracts and pulls downwards, allowing air to flow into the lungs. This process is regulated by a group of neurons in the brainstem known as the pre-Bötzinger complex.
Nasal vs. Mouth Breathing
Dr. Feldman explains that while nasal breathing is the norm at rest due to its efficiency in filtering and warming the air, mouth breathing becomes necessary during physical exertion when larger volumes of air are needed. However, the contraction of the diaphragm and intercostal muscles is largely independent of whether we breathe through our nose or mouth.
Brain Centers and Breathing
The discussion evolves into the brain centers that control respiration. The pre-Bötzinger complex is known for generating rhythmic breathing patterns, while another oscillator, located near the facial nucleus, is responsible for active expiration, especially during exercise. Dr. Feldman highlights the evolutionary significance of these mechanisms, particularly the diaphragm, which enables mammals to breathe efficiently compared to amphibians and reptiles.
The Importance of Deep Breathing
Interestingly, humans naturally take deep breaths or “sigh” approximately every five minutes. This physiological sigh is crucial for maintaining lung health by preventing the collapse of alveoli. Dr. Feldman notes that during early mechanical ventilation practices, it was discovered that larger breaths could significantly improve patient outcomes, underscoring the importance of deep breathing in maintaining lung function.
Breathing and Emotional Regulation
Breathing is not just a physiological necessity; it also plays a critical role in emotional regulation. Dr. Feldman shares insights from his research involving rodents, where teaching them to breathe slowly resulted in reduced fear responses. This suggests that controlled breathing practices can influence emotional and cognitive states.
Connections Between Breathing and Brain Function
Breathing affects various brain functions and emotional states. Changes in breathing patterns can influence how we feel, and conversely, our emotional state can alter our breathing. The vagus nerve, which carries signals from the lungs to the brain, plays a critical role in this interaction. Dr. Feldman also discusses how slow breathing can help restore balanced carbon dioxide levels, which is essential for mental well-being.
Practical Applications of Breathing Techniques
Dr. Huberman shares his personal practice of using box breathing, a method that involves inhaling, holding, and exhaling for equal counts (e.g., 5 seconds each). Many people find that even short durations of focused breathing can enhance their emotional and cognitive states. Dr. Feldman encourages more people to explore various breathing practices, emphasizing their accessibility and potential benefits.
Supplementation and Cognitive Function
Concluding the discussion, Dr. Feldman and Dr. Huberman touch upon the role of supplementation in cognitive function, particularly magnesium. Magnesium threonate has been shown to enhance cognitive capabilities and improve sleep quality, demonstrating its potential benefits for mental health.
Key Takeaways
- Breathing is essential for oxygen intake and carbon dioxide removal, regulated by the diaphragm and neural centers in the brain.
- Both nasal and mouth breathing serve distinct functions, with nasal breathing being more efficient at rest.
- Deep breathing helps maintain lung health by preventing alveolar collapse.
- Breathing practices can significantly influence emotional regulation and cognitive function.
- Supplements like magnesium threonate may enhance cognitive performance and support mental health.
Conclusion
The intricate relationship between breathing and brain function highlights the importance of understanding our respiratory processes. By incorporating mindful breathing techniques and considering the role of supplements, individuals can potentially enhance both their physical and mental health. As Dr. Feldman noted, exploring simple breathing practices can lead to remarkable benefits without any cost.
For more insights on breathing and its impact on health, stay tuned for future discussions on the Huberman Lab podcast.
