This Changed my Opinion on High Protein Diets (easy fix)
Thomas DeLauerPublished on October 26, 2026
Summary authored by editor@wellifi.com
TLDR Summary
High-protein diets may lead to a glycine deficiency, impacting recovery and joint health. Supplementing with glycine through collagen and creatine can enhance overall health and recovery capabilities.
Key Points
- High-protein diets often lack sufficient glycine.
- Glycine is essential for creatine synthesis, collagen formation, and antioxidant production.
- Supplementing with creatine can free up glycine for other important functions.
- Bone broth and collagen supplements are excellent sources of glycine.
- Addressing glycine deficiency can improve recovery, joint health, and sleep quality.
Why Glycine is Essential for Your High-Protein Diet
If you consume a high-protein diet, you are likely familiar with foods such as chicken, steak, eggs, Greek yogurt, and protein shakes. These foods are excellent for muscle building and meeting your protein needs. However, there is one amino acid that is not sufficiently provided by any of these foods, yet your body requires approximately 10 grams more of it daily. In the past, our ancestors consumed this amino acid regularly, but today, it is often lacking in our diets. This gap has more significant implications than you might realize.
The Glycine Gap in Modern Diets
Despite consuming large amounts of protein, you may still feel unwell. One reason for this could be that your body is competing to produce creatine and repair connective tissues due to insufficient glycine intake. This might sound complex, but I will break it down for you.
Today, we will discuss:
- Why your current diet may not provide enough amino acids.
- The three systems that are affected by this deficiency and why even a high-protein diet can lead to problems.
- The simplest ways to address this deficiency without eliminating protein from your diet.
The Importance of Glycine
The amino acid we are talking about is glycine, which may seem insignificant as it is categorized as a non-essential amino acid, meaning your body can produce it. However, recent research indicates that your body only generates about 3 grams of glycine per day, while your metabolic needs require approximately 15 grams. This results in a daily deficit of about 10 grams.
The authors of a study published in the Journal of Biosciences suggest that glycine should be classified as an essential amino acid since our internal production cannot meet our requirements.
One critical reason why glycine is even more important today is that we have stopped consuming traditional foods like skin, tendons, and bone broth, which are rich in glycine. While muscle meats are delicious, they provide little to no glycine compared to what our bodies need. Therefore, as you consume more protein from conventional sources, the gap between glycine intake and our requirements widens.
How to Supplement Glycine in Your Diet
One effective way to reduce the pressure on your body's glycine levels is by using creatine supplements, as glycine is required for creatine synthesis. By supplementing with creatine, the glycine that would otherwise be utilized for creatine production is preserved for other essential functions.
Glycine plays a vital role not only in creatine synthesis but also in glutathione production and collagen formation, which is crucial for repairing connective tissues. Therefore, when there is a glycine deficit, the synthesis of creatine, collagen, and glutathione is compromised.
The Impact of a High-Protein Diet
For those on a high-protein diet, the first systems to be affected are often connective tissue repair and antioxidant capacity, resulting in joint pain and poor sleep quality. This issue may not be immediately visible, but it can significantly impact your overall health and recovery.
Addressing Glycine Deficiency
If you're looking to increase your glycine intake, consider adding collagen supplements to your routine. A single serving of collagen can provide 3 to 5 grams of glycine. Additionally, consuming bone broth, skin from chicken, or soft bone parts from beef can help you get closer to your glycine needs.
Moreover, combining collagen with creatine supplementation can significantly enhance your recovery and performance. The quality of collagen is also crucial, and studies show that various sources, including hydrolyzed collagen powder and gelatin, provide similar benefits.
Conclusion
In summary, while your high-protein diet may be meeting your muscle-building needs, it is likely falling short in providing the necessary glycine for collagen synthesis, antioxidant production, and overall recovery. By strategically supplementing with glycine through collagen, bone broth, and creatine, you can enhance your body’s recovery capabilities significantly.
Always consider your individual needs and how you can incorporate glycine into your diet effectively for optimal health.